Epigenetic Landscapes: Drawings as Metaphor

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By Susan Merrill Squier ’72

Published Nov. 30, 2017

The epigenetic landscape is a metaphor for how gene regulation modulates cellular development. It fell out of favor in the 1960s but is now in use again in big-data genomic research. Epigenetic Landscapes (Duke University Press) follows the model’s cultural trail, from its first depiction by artist John Piper to its use in landscape architecture and bioArt.

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PAW's July/August 2025 issue cover, featuring a photo of people dressed in orange and black, marching in the P-rade, and the headline: Reunions, Back in Orange & Black.
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On the cover: Wilton Virgo ’00 and his classmates celebrate during the P-rade.